What you need for either is the free K-Lite Mega Codec Pack.

MediaShout and EasyWorship require some extra work to get them to playback quicktime content but it can be done. Now, when it comes to quicktime, ProPresenter, being a Mac application, will play it natively. You can then add this into any of the worship softwares we've mentioned. You can, however, save your keynote presentations as either powerpoint slideshows or a series of jpeg images. In other words, programs cannot tap into it and use its functionality. Keynote is a little different than powerpoint, in that it does not have an API. ProPresenter is working on a windows version, and although they haven't released a beta yet, they have announced an expected release for this summer. Both EasyWorship and MediaShout are working on a Mac version, but neither is to the Beta testing stage yet. The three biggest names in commercial worship software right now are EasyWorship, MediaShout, and ProPresenter. It isn't a high performer, but it is cross-platform and will display song lyrics and bible passages over still and moving backgrounds. There is a cross-platform commercial solution, Live Worship. I don't know of an open-source cross-platform solution.

Upgrading from media shout 4 to 6